CALCOCO1 antibody (AA 462-691)

Catalog No. ABIN6137858

Product Details anti-CALCOCO1 Antibody

Target: CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))

Binding Specificity: AA 462-691

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CALCOCO1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LVQLSESKRE LTELRSALRV LQKEKEQLQE EKQELLEYMR KLEARLEKVA DEKWNEDATT EDEEAAVGLS CPAALTDSED ESPEDMRLPP YGLCERGDPG SSPAGPREAS PLVVISQPAP ISPHLSGPAE DSSSDSEAED EKSVLMAAVQ SGGEEANLLL PELGSAFYDM ASGFTVGTLS ETSTGGPATP TWKECPICKE RFPAESDKDA LEDHMDGHFF FSTQDPFTFE

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 462-691 of human CALCOCO1 (NP_065949.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CALCOCO1

Target: CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))

Alternative Name: CALCOCO1 (CALCOCO1 Products)

Synonyms: Cocoa antibody, calphoglin antibody, fa11a10 antibody, wu:fa11a10 antibody, CALCOCO1 antibody, Xdsg antibody, cocoa antibody, dsgc antibody, pp13275 antibody, 1810009B06Rik antibody, Gcap11 antibody, mKIAA1536 antibody, calcium binding and coiled-coil domain 1 antibody, calcium binding and coiled-coil domain 1a antibody, calcium binding and coiled-coil domain 1 S homeolog antibody, calcium binding and coiled-coil domain 1 L homeolog antibody, calcium binding and coiled coil domain 1 antibody, CALCOCO1 antibody, calcoco1a antibody, calcoco1.S antibody, calcoco1.L antibody, Calcoco1 antibody

Background: Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR. Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions (By similarity. In association with CCAR1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells.,CALCOCO1,Cocoa,PP13275,calphoglin,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,Neuroscience,Calcium Signaling,CALCOCO1

Molecular Weight: 67 kDa/70 kDa/77 kDa

Gene ID: 57658

UniProt: Q9P1Z2

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Chromatin Binding