CALCOCO1 antibody (AA 462-691)
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- Target See all CALCOCO1 Antibodies
- CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))
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Binding Specificity
- AA 462-691
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CALCOCO1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LVQLSESKRE LTELRSALRV LQKEKEQLQE EKQELLEYMR KLEARLEKVA DEKWNEDATT EDEEAAVGLS CPAALTDSED ESPEDMRLPP YGLCERGDPG SSPAGPREAS PLVVISQPAP ISPHLSGPAE DSSSDSEAED EKSVLMAAVQ SGGEEANLLL PELGSAFYDM ASGFTVGTLS ETSTGGPATP TWKECPICKE RFPAESDKDA LEDHMDGHFF FSTQDPFTFE
- Cross-Reactivity
- Human, Mouse
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 462-691 of human CALCOCO1 (NP_065949.1).
- Isotype
- IgG
- Top Product
- Discover our top product CALCOCO1 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))
- Alternative Name
- CALCOCO1 (CALCOCO1 Products)
- Synonyms
- Cocoa antibody, calphoglin antibody, fa11a10 antibody, wu:fa11a10 antibody, CALCOCO1 antibody, Xdsg antibody, cocoa antibody, dsgc antibody, pp13275 antibody, 1810009B06Rik antibody, Gcap11 antibody, mKIAA1536 antibody, calcium binding and coiled-coil domain 1 antibody, calcium binding and coiled-coil domain 1a antibody, calcium binding and coiled-coil domain 1 S homeolog antibody, calcium binding and coiled-coil domain 1 L homeolog antibody, calcium binding and coiled coil domain 1 antibody, CALCOCO1 antibody, calcoco1a antibody, calcoco1.S antibody, calcoco1.L antibody, Calcoco1 antibody
- Background
- Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR. Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions (By similarity. In association with CCAR1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells.,CALCOCO1,Cocoa,PP13275,calphoglin,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,Neuroscience,Calcium Signaling,CALCOCO1
- Molecular Weight
- 67 kDa/70 kDa/77 kDa
- Gene ID
- 57658
- UniProt
- Q9P1Z2
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Chromatin Binding
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