CYP3A5 antibody (AA 233-502)
-
- Target See all CYP3A5 Antibodies
- CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))
-
Binding Specificity
- AA 233-502
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This CYP3A5 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- FEALNVSLFP KDTINFLSKS VNRMKKSRLN DKQKHRLDFL QLMIDSQNSK ETESHKALSD LELAAQSIIF IFAGYETTSS VLSFTLYELA THPDVQQKLQ KEIDAVLPNK APPTYDAVVQ MEYLDMVVNE TLRLFPVAIR LERTCKKDVE INGVFIPKGS MVVIPTYALH HDPKYWTEPE EFRPERFSKK KDSIDPYIYT PFGTGPRNCI GMRFALMNMK LALIRVLQNF SFKPCKETQI PLKLDTQGLL QPEKPIVLKV DSRDGTLSGE
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 233-502 of human CYP3A5 (NP_000768.1).
- Isotype
- IgG
- Top Product
- Discover our top product CYP3A5 Primary Antibody
-
-
- Application Notes
- WB,1:500 - 1:2000
- Comment
-
HIGH QUALITY
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))
- Alternative Name
- CYP3A5 (CYP3A5 Products)
- Synonyms
- CP35 antibody, CYPIIIA5 antibody, P450PCN3 antibody, PCN3 antibody, cytochrome P450 family 3 subfamily A member 5 antibody, CYP3A5 antibody
- Background
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.,CYP3A5,CP35,CYPIIIA5,P450PCN3,PCN3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Lipid Metabolism,Cytochromes,Lipases,Drug metabolism,Cardiovascular,Lipids,CYP3A5
- Molecular Weight
- 15 kDa/57 kDa
- Gene ID
- 1577
- UniProt
- P20815
- Pathways
- Steroid Hormone Biosynthesis
-