Desmocollin 2 antibody (AA 520-690)
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- Target See all Desmocollin 2 (DSC2) Antibodies
- Desmocollin 2 (DSC2)
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Binding Specificity
- AA 520-690
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Desmocollin 2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- IDENTGSIKV FRSLDREAET IKNGIYNITV LASDQGGRTC TGTLGIILQD VNDNSPFIPK KTVIICKPTM SSAEIVAVDP DEPIHGPPFD FSLESSTSEV QRMWRLKAIN DTAARLSYQN DPPFGSYVVP ITVRDRLGMS SVTSLDVTLC DCITENDCTH RVDPRIGGGG V
- Cross-Reactivity
- Human
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 520-690 of human DSC2 (NP_077740.1).
- Isotype
- IgG
- Top Product
- Discover our top product DSC2 Primary Antibody
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- Application Notes
- WB,1:1000 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Desmocollin 2 (DSC2)
- Alternative Name
- DSC2 (DSC2 Products)
- Synonyms
- ARVD11 antibody, CDHF2 antibody, DG2 antibody, DGII/III antibody, DSC3 antibody, AW228162 antibody, Dsc2a antibody, Dsc2b antibody, DSC2 antibody, desmocollin 2 antibody, DSC2 antibody, Dsc2 antibody
- Background
- This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.,DSC2,ARVD11,CDHF2,DG2,DGII/III,DSC3,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Cytoskeleton,Extracellular Matrix,Cardiovascular,Heart,Cardiac arrhythmias,DSC2
- Molecular Weight
- 93 kDa/99 kDa
- Gene ID
- 1824
- UniProt
- Q02487
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