EIF4E2 antibody (AA 1-240)

Catalog No. ABIN6140086

Product Details anti-EIF4E2 Antibody

Target: EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))

Binding Specificity: AA 1-240

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF4E2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MNNKFDALKD DDSGDHDQNE ENSTQKDGEK EKTERDKNQS SSKRKAVVPG PAEHPLQYNY TFWYSRRTPG RPTSSQSYEQ NIKQIGTFAS VEQFWRFYSH MVRPGDLTGH SDFHLFKEGI KPMWEDDANK NGGKWIIRLR KGLASRCWEN LILAMLGEQF MVGEEICGAV VSVRFQEDII SIWNKTASDQ ATTARIRDTL RRVLNLPPNT IMEYKTHTDS IKMPGRLGPQ RLLFQNLWKP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human EIF4E2 (NP_004837.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EIF4E2

Target: EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))

Alternative Name: EIF4E2 (EIF4E2 Products)

Synonyms: 4E-LP antibody, 4EHP antibody, EIF4EL3 antibody, IF4e antibody, Eif4el3 antibody, EIF4E2 antibody, id:ibd1007 antibody, zgc:110542 antibody, zgc:158544 antibody, MGC115622 antibody, 2700069E09Rik antibody, AI036339 antibody, AV129531 antibody, D0H0S6743E antibody, eukaryotic translation initiation factor 4E family member 2 antibody, eukaryotic translation initiation factor 4E member 2 antibody, eukaryotic translation initiation factor 4E family member 2 L homeolog antibody, EIF4E2 antibody, Eif4e2 antibody, eif4e2 antibody, eif4e2.L antibody

Background: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation. Acts as a repressor of translation initiation. In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3, suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap (By similarity. In P-bodies, component of a complex that promotes miRNA-mediated translational repression.,EIF4E2,4E-LP,4EHP,EIF4EL3,IF4e,h4EHP,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,EIF4E2

Molecular Weight: 27 kDa/28 kDa

Gene ID: 9470

UniProt: O60573

Pathways: SARS-CoV-2 Protein Interactome