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EIF4G1 antibody (AA 400-500)
EIF4G1
Reactivity: Human
IHC, WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-EIF4G1 Antibody
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Target
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EIF4G1
(Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))
Binding Specificity
All epitopes for EIF4G1 antibodies
AA 400-500
Reactivity
All reactivities for EIF4G1 antibodies
Human
Host
All hosts for EIF4G1 antibodies
Rabbit
Clonality
All clonalities for EIF4G1 antibodies
Polyclonal
Conjugate
All conjugates for EIF4G1 antibodies
This EIF4G1 antibody is un-conjugated
Application
All applications for EIF4G1 antibodies
Immunohistochemistry (IHC), Western Blotting (WB)
Sequence
PEELLNGAPS PPAVDLSPVS EPEEQAKEVT ASMAPPTIPS ATPATAPSAT SPAQEEEMEE EEEEEEGEAG EAGEAESEKG GEELLPPEST PIPANLSQNL E
Cross-Reactivity
Human
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human EIF4G (NP_886553.3).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:1000,IHC,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for EIF4G1
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Target
EIF4G1
(Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))
Alternative Name
EIF4G1 (EIF4G1 Products )
Synonyms
EIF4GI antibody, CG10811 antibody, Dmel\\CG10811 antibody, EIF4G antibody, Eif4G antibody, deIF4G antibody, eIF-4G antibody, eIF4g antibody, p200 antibody, EIF4G1 antibody, wu:fb50a05 antibody, wu:fc60b06 antibody, eif4g antibody, CUCUMOVIRUS MULTIPLICATION 2 antibody, CUM2 antibody, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G antibody, eukaryotic translation initiation factor 4G antibody, DDBDRAFT_0217646 antibody, DDBDRAFT_0217647 antibody, DDBDRAFT_0234257 antibody, DDB_0217646 antibody, DDB_0217647 antibody, DDB_0234257 antibody, NV18824 antibody, EIF-4G1 antibody, EIF4F antibody, P220 antibody, PARK18 antibody, p220 antibody, E030015G23Rik antibody, eIF4GI antibody, eukaryotic translation initiation factor 4 gamma 1 antibody, eukaryotic translation initiation factor 4G antibody, eukaryotic translation initiation factor 4 gamma, 1a antibody, eukaryotic translation initiation factor 4 gamma, 1 S homeolog antibody, eukaryotic initiation factor antibody, eukaryotic translation initiation factor 4 gamma antibody, eukaryotic translation initiation factor 4 gamma, 1 antibody, eukaryotic translation initiation factor 4, gamma 1 antibody, EIF4G1 antibody, eIF4G antibody, eif4g1a antibody, LOC704923 antibody, eif4g1.S antibody, EIF4G antibody, eIF4g antibody, Eif4g antibody, Eif4g1 antibody
Background
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.,EIF4G1,EIF-4G1,EIF4F,EIF4G,EIF4GI,P220,PARK18,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,PI3K-Akt Signaling Pathway,Immunology & Inflammation,Akt downstream targets,EIF4G1
Molecular Weight
154 kDa/158 kDa/166 kDa/171 kDa/175 kDa/176 kDa
Gene ID
1981
UniProt
Q04637
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