Envoplakin antibody (AA 1784-2033)

Catalog No. ABIN6140350

Product Details anti-Envoplakin Antibody

Target: Envoplakin (EVPL)

Binding Specificity: AA 1784-2033

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Envoplakin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TKPSSSLSIG SIISKSPLAS PAPQSTSFFS PSFSLGLGDD SFPIAGIYDT TTDNKCSIKT AVAKNMLDPI TGQKLLEAQA ATGGIVDLLS RERYSVHKAM ERGLIENTST QRLLNAQKAF TGIEDPVTKK RLSVGEAVQK GWMPRESVLP HLQVQHLTGG LIDPKRTGRI PIQQALLSGM ISEELAQLLQ DESSYEKDLT DPISKERLSY KEAMGRCRKD PLSGLLLLPA ALEGYRCYRS ASPTVPRSLR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1784-2033 of human EVPL (NP_001979.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Envoplakin

Target: Envoplakin (EVPL)

Alternative Name: EVPL (EVPL Products)

Background: This gene encodes a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. This gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against the encoded protein.,EVPL,EVPK,EVPL

Molecular Weight: 231 kDa

Gene ID: 2125

UniProt: Q92817