FBXO22 antibody (AA 104-403)

Catalog No. ABIN6140516

Product Details anti-FBXO22 Antibody

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Binding Specificity: AA 104-403

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO22 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YMADSETFIS LEECRGHKRA RKRTSMETAL ALEKLFPKQC QVLGIVTPGI VVTPMGSGSN RPQEIEIGES GFALLFPQIE GIKIQPFHFI KDPKNLTLER HQLTEVGLLD NPELRVVLVF GYNCCKVGAS NYLQQVVSTF SDMNIILAGG QVDNLSSLTS EKNPLDIDAS GVVGLSFSGH RIQSATVLLN EDVSDEKTAE AAMQRLKAAN IPEHNTIGFM FACVGRGFQY YRAKGNVEAD AFRKFFPSVP LFGFFGNGEI GCDRIVTGNF ILRKCNEVKD DDLFHSYTTI MALIHLGSSK

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 104-403 of human FBXO22 (NP_671717.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FBXO22

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Alternative Name: FBXO22 (FBXO22 Products)

Synonyms: FBXO22 antibody, DKFZp469L0535 antibody, fbxo22 antibody, MGC146708 antibody, si:busm1-132m23.3 antibody, FBX22 antibody, FISTC1 antibody, 0610033L19Rik antibody, 1600016C16Rik antibody, F-box protein 22 antibody, FBXO22 antibody, fbxo22 antibody, Fbxo22 antibody

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants.,FBXO22,FBX22,FISTC1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,FBXO22

Molecular Weight: 4 kDa/30 kDa/44 kDa

Gene ID: 26263

UniProt: Q8NEZ5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development