GNB2 antibody (AA 1-340)

Catalog No. ABIN6141223

Product Details anti-GNB2 Antibody

Target: GNB2 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2 (GNB2))

Binding Specificity: AA 1-340

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MSELEQLRQE AEQLRNQIRD ARKACGDSTL TQITAGLDPV GRIQMRTRRT LRGHLAKIYA MHWGTDSRLL VSASQDGKLI IWDSYTTNKV HAIPLRSSWV MTCAYAPSGN FVACGGLDNI CSIYSLKTRE GNVRVSRELP GHTGYLSCCR FLDDNQIITS SGDTTCALWD IETGQQTVGF AGHSGDVMSL SLAPDGRTFV SGACDASIKL WDVRDSMCRQ TFIGHESDIN AVAFFPNGYA FTTGSDDATC RLFDLRADQE LLMYSHDNII CGITSVAFSR SGRLLLAGYD DFNCNIWDAM KGDRAGVLAG HDNRVSCLGV TDDGMAVATG SWDSFLKIWN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human GNB2 (NP_005264.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GNB2

Target: GNB2 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2 (GNB2))

Alternative Name: GNB2 (GNB2 Products)

Synonyms: XGB1 antibody, XGbeta1 antibody, gnb2 antibody, Gnb-2 antibody, im:7138539 antibody, zgc:113357 antibody, guanine nucleotide binding protein (G protein), beta polypeptide 1 antibody, G protein subunit beta 2 antibody, guanine nucleotide binding protein (G protein), beta 2 antibody, guanine nucleotide binding protein (G protein), beta polypeptide 2 antibody, gnb1 antibody, GNB2 antibody, Gnb2 antibody, gnb2 antibody

Background: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR.,GNB2,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,G protein signaling,mTOR Signaling Pathway,Phospholipase Signaling Pathway,MAPK-JNK Signaling Pathway,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,GNB2

Molecular Weight: 25 kDa/37 kDa

Gene ID: 2783

UniProt: P62879

Pathways: Myometrial Relaxation and Contraction