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HPGD antibody (AA 1-266)
HPGD
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HPGD Antibody
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Target
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HPGD
(Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))
Binding Specificity
All epitopes for HPGD antibodies
AA 1-266
Reactivity
All reactivities for HPGD antibodies
Human
Host
All hosts for HPGD antibodies
Rabbit
Clonality
All clonalities for HPGD antibodies
Polyclonal
Conjugate
All conjugates for HPGD antibodies
This HPGD antibody is un-conjugated
Application
All applications for HPGD antibodies
Western Blotting (WB)
Sequence
MHVNGKVALV TGAAQGIGRA FAEALLLKGA KVALVDWNLE AGVQCKAALD EQFEPQKTLF IQCDVADQQQ LRDTFRKVVD HFGRLDILVN NAGVNNEKNW EKTLQINLVS VISGTYLGLD YMSKQNGGEG GIIINMSSLA GLMPVAQQPV YCASKHGIVG FTRSAALAAN LMNSGVRLNA ICPGFVNTAI LESIEKEENM GQYIEYKDHI KDMIKYYGIL DPPLIANGLI TLIEDDALNG AIMKITTSKG IHFQDYDTTP FQAKTQ
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-266 of human 15-PGDH/15-PGDH/HPGD (NP_000851.2).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
References for anti-HPGD antibody (ABIN6141966)
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Wu, Liu, Yang, Liu, Liu, Wang, Xiong, Yu, Huang, Zhuang : "Association of 15-hydroxyprostaglandin dehydrogenate and poor prognosis of obese breast cancer patients. " in: Oncotarget , Vol. 8 , Issue 14 , pp. 22842-22853 , (2017 ) (PubMed ).
Target Details for HPGD
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Target
HPGD
(Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))
Alternative Name
HPGD (HPGD Products )
Synonyms
CBR antibody, SDR21C1 antibody, hCBR1 antibody, 15-PGDH antibody, PGDH antibody, PGDH1 antibody, PHOAR1 antibody, SDR36C1 antibody, MGC80546 antibody, MGC79454 antibody, AV026552 antibody, carbonyl reductase 1 antibody, 15-hydroxyprostaglandin dehydrogenase antibody, hydroxyprostaglandin dehydrogenase 15-(NAD) antibody, 15-hydroxyprostaglandin dehydrogenase L homeolog antibody, hydroxyprostaglandin dehydrogenase 15 (NAD) antibody, CBR1 antibody, HPGD antibody, hpgd.L antibody, hpgd antibody, pgdh antibody, Hpgd antibody, PTRG_03214 antibody, VDBG_09957 antibody
Background
This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.,HPGD,15-PGDH,PGDH,PGDH1,PHOAR1,SDR36C1,Signal Transduction,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,HPGD
Molecular Weight
15 kDa/19 kDa/21 kDa/28 kDa
Gene ID
3248
UniProt
P15428
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