HYAL1 antibody (AA 136-435)

Catalog No. ABIN6142094

Product Details anti-HYAL1 Antibody

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Binding Specificity: AA 136-435

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HYAL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RWAFNWDTKD IYRQRSRALV QAQHPDWPAP QVEAVAQDQF QGAARAWMAG TLQLGRALRP RGLWGFYGFP DCYNYDFLSP NYTGQCPSGI RAQNDQLGWL WGQSRALYPS IYMPAVLEGT GKSQMYVQHR VAEAFRVAVA AGDPNLPVLP YVQIFYDTTN HFLPLDELEH SLGESAAQGA AGVVLWVSWE NTRTKESCQA IKEYMDTTLG PFILNVTSGA LLCSQALCSG HGRCVRRTSH PKALLLLNPA SFSIQLTPGG GPLSLRGALS LEDQAQMAVE FKCRCYPGWQ APWCERKSMW

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 136-435 of human HYAL1 (NP_149349.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HYAL1

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Alternative Name: HYAL1 (HYAL1 Products)

Synonyms: HYAL-1 antibody, LUCA1 antibody, NAT6 antibody, Hya1 antibody, Hyal-1 antibody, hyaluronoglucosaminidase 1 antibody, HYAL1 antibody, Hyal1 antibody

Background: This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.,HYAL1,HYAL-1,LUCA1,MPS9,NAT6,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,HYAL1

Molecular Weight: 10 kDa/19 kDa/23 kDa/27 kDa/37 kDa/45 kDa/48 kDa

Gene ID: 3373

UniProt: Q12794

Pathways: Glycosaminoglycan Metabolic Process