MAP2K5 antibody (AA 1-190)

Catalog No. ABIN6143488

Product Details anti-MAP2K5 Antibody

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Binding Specificity: AA 1-190

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MLWLALGPFP AMENQVLVIR IKIPNSGAVD WTVHSGPQLL FRDVLDVIGQ VLPEATTTAF EYEDEDGDRI TVRSDEEMKA MLSYYYSTVM EQQVNGQLIE PLQIFPRACK PPGERNIHGL KVNTRAGPSQ HSSPAVSDSL PSNSLKKSSA ELKKILANGQ MNEQDIRYRD TLGHGNGGTV YKAYHVPSGK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MEK5 (NP_660143.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MAP2K5

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Alternative Name: MAP2K5 (MAP2K5 Products)

Synonyms: Mek5 antibody, HsT17454 antibody, MAPKK5 antibody, MEK5 antibody, PRKMK5 antibody, AI324775 antibody, AI428457 antibody, Mapkk5 antibody, Prkmk5 antibody, fb73f02 antibody, wu:fb73f02 antibody, zgc:172137 antibody, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 antibody, ATMAP2K_ALPHA antibody, ATMEK5 antibody, ATMKK5 antibody, MAP KINASE KINASE 5 antibody, MAP kinase kinase 5 antibody, MAP2K_A antibody, mitogen activated protein kinase kinase 5 antibody, mitogen-activated protein kinase kinase 5 antibody, mitogen-activated protein kinase kinase 5 L homeolog antibody, MAP kinase kinase 5 antibody, Map2k5 antibody, MAP2K5 antibody, map2k5 antibody, map2k5.L antibody, MKK5 antibody

Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.,MAP2K5,HsT17454,MAPKK5,MEK5,PRKMK5,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,Cardiovascular,Heart,Cardiogenesis,MAP2K5

Molecular Weight: 46 kDa/48 kDa/49 kDa/50 kDa

Gene ID: 5607

UniProt: Q13163

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway