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MDC1 antibody (AA 1-100)

MDC1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6143659
  • Target See all MDC1 Antibodies
    MDC1 (Mdc1 (MDC1))
    Binding Specificity
    • 22
    • 16
    • 15
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivity
    • 59
    • 54
    • 16
    • 12
    • 11
    • 2
    • 1
    • 1
    Human
    Host
    • 49
    • 37
    Rabbit
    Clonality
    • 49
    • 37
    Polyclonal
    Conjugate
    • 29
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MDC1 antibody is un-conjugated
    Application
    • 66
    • 30
    • 14
    • 13
    • 13
    • 13
    • 11
    • 10
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequence
    MEDTQAIDWD VEEEEETEQS SESLRCNVEP VGRLHIFSGA HGPEKDFPLH LGKNVVGRMP DCSVALPFPS ISKQHAEIEI LAWDKAPILR DCGSLNGTQI
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MDC1 (NP_055456.2).
    Isotype
    IgG
    Top Product
    Discover our top product MDC1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MDC1 (Mdc1 (MDC1))
    Alternative Name
    MDC1 (MDC1 Products)
    Synonyms
    6820401C03 antibody, AA413496 antibody, Nfbd1 antibody, mKIAA0170 antibody, NFBD1 antibody, mediator of DNA damage checkpoint 1 antibody, mediator of DNA-damage checkpoint 1 antibody, Mdc1 antibody, MDC1 antibody
    Background
    The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.,MDC1,NFBD1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MDC1
    Molecular Weight
    116 kDa/195 kDa/197 kDa/226 kDa
    Gene ID
    9656
    UniProt
    Q14676
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