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MKL1 antibody (AA 1-280)
MKL1
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MKL1 Antibody
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Target
See all MKL1 Antibodies
MKL1
(Megakaryoblastic Leukemia (Translocation) 1 (MKL1))
Binding Specificity
All epitopes for MKL1 antibodies
AA 1-280
Reactivity
All reactivities for MKL1 antibodies
Human
Host
All hosts for MKL1 antibodies
Rabbit
Clonality
All clonalities for MKL1 antibodies
Polyclonal
Conjugate
All conjugates for MKL1 antibodies
This MKL1 antibody is un-conjugated
Application
All applications for MKL1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Sequence
MPPLKSPAAF HEQRRSLERA RTEDYLKRKI RSRPERSELV RMHILEETSA EPSLQAKQLK LKRARLADDL NEKIAQRPGP MELVEKNILP VESSLKEAII VGQVNYPKVA DSSSFDEDSS DALSPEQPAS HESQGSVPSP LEARVSEPLL SATSASPTQV VSQLPMGRDS REMLFLAEQP PLPPPPLLPP SLTNGTTIPT AKSTPTLIKQ SQPKSASEKS QRSKKAKELK PKVKKLKYHQ YIPPDQKQDR GAPPMDSSYA KILQQQQLFL QLQILNQQQQ
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human MKL1 (NP_065882.1).
Isotype
IgG
Top Product
Discover our top product MKL1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for MKL1
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Target
MKL1
(Megakaryoblastic Leukemia (Translocation) 1 (MKL1))
Alternative Name
MKL1 (MKL1 Products )
Synonyms
MKL1 antibody, BSAC antibody, MAL antibody, MRTF-A antibody, Mrtf-a antibody, mrtf-a antibody, mrtfa antibody, AI852829 antibody, AMKL antibody, AW743281 antibody, AW821984 antibody, Bsac antibody, Mal antibody, Mrtf-A antibody, megakaryoblastic leukemia (translocation) 1 antibody, megakaryoblastic leukemia 1 protein antibody, megakaryoblastic leukemia (translocation) 1 S homeolog antibody, MKL (megakaryoblastic leukemia)/myocardin-like 1 antibody, MKL1 antibody, mkl1 antibody, Mkl1 antibody, mkl1.S antibody
Background
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.,MKL1,BSAC,MAL,MRTF-A,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cytoskeleton,Endocrine & Metabolism,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Heart,Cardiogenesis,MKL1
Molecular Weight
98 kDa
Gene ID
57591
UniProt
Q969V6
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