Cytochrome b antibody (AA 1-100)

Catalog No. ABIN6225085

Product Details anti-Cytochrome b Antibody

Target: Cytochrome b (MT-CYB) (Mitochondrially Encoded Cytochrome B (MT-CYB))

Binding Specificity: AA 1-100

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytochrome b antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MTNMRKTHPL FKIINHSFID LPAPSNISSW WNFGSLLGVC LMVQIITGLF LAMHYTSDTM TAFSSVTHIC RDVNYGWLIR YMHANGASMF FICLFLHVGR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of mouse MT-CYB (NP_904340.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-Cytochrome b antibody (ABIN6225085)

Li, Zhou, Li, Li, Long, Chen, Zhang, Li, Feng: "WITHDRAWN:Mitochondrial targeting of HIF-1α inhibits hypoxia-induced apoptosis independently of its transcriptional activity." in: Free radical biology & medicine, (2018) (PubMed).

Hu, Nie, Chen, Xie, Fan, Wang, Long, Yan, Zhong, Yan: "Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." in: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).

Target Details for Cytochrome b

Target: Cytochrome b (MT-CYB) (Mitochondrially Encoded Cytochrome B (MT-CYB))

Alternative Name: Mt-Cyb (MT-CYB Products)

Synonyms: cytB antibody, cytb antibody, MTCYB antibody, cytochrome b antibody, CYTB antibody

Background: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.,MT-CYB,MTCYB,CYTB,Mt-Cyb,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Neuroscience,Neurodegenerative Diseases,Mt-Cyb

Molecular Weight: 43 kDa

Gene ID: 17711

UniProt: P00158

Pathways: Proton Transport