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PCSK5 antibody (AA 601-913)

PCSK5 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6145326
  • Target See all PCSK5 Antibodies
    PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))
    Binding Specificity
    • 14
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 601-913
    Reactivity
    • 33
    • 16
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 36
    • 1
    • 1
    Rabbit
    Clonality
    • 37
    • 1
    Polyclonal
    Conjugate
    • 13
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCSK5 antibody is un-conjugated
    Application
    • 24
    • 20
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    QPYSPTNEFP KVERFRYSRV EDPTDDYGTE DYAGPCDPEC SEVGCDGPGP DHCNDCLHYY YKLKNNTRIC VSSCPPGHYH ADKKRCRKCA PNCESCFGSH GDQCMSCKYG YFLNEETNSC VTHCPDGSYQ DTKKNLCRKC SENCKTCTEF HNCTECRDGL SLQGSRCSVS CEDGRYFNGQ DCQPCHRFCA TCAGAGADGC INCTEGYFME DGRCVQSCSI SYYFDHSSEN GYKSCKKCDI SCLTCNGPGF KNCTSCPSGY LLDLGMCQMG AICKDATEES WAEGGFCMLV KKNNLCQRKV LQQLCCKTCT FQG
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 601-913 of human PCSK5 (NP_006191.2).
    Isotype
    IgG
    Top Product
    Discover our top product PCSK5 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))
    Alternative Name
    PCSK5 (PCSK5 Products)
    Synonyms
    PC5 antibody, PC6 antibody, PC6A antibody, SPC6 antibody, subtilase antibody, PC5/6A antibody, PC5A antibody, b2b1549Clo antibody, b2b585Clo antibody, Pc5 antibody, fur2 antibody, spc6 antibody, spc6A antibody, MGC98915 antibody, PCSK5 antibody, pc6 antibody, spc6a antibody, pcsk5 antibody, zgc:165659 antibody, proprotein convertase subtilisin/kexin type 5 antibody, proprotein convertase subtilisin/kexin type 5 S homeolog antibody, proprotein convertase subtilisin/kexin type 5b antibody, PCSK5 antibody, Pcsk5 antibody, pcsk5.S antibody, LOC528098 antibody, pcsk5 antibody, pcsk5b antibody
    Background
    This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER. It then sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. This encoded protein is widely expressed and one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Alternative splicing results in multiple transcript variants, some of which encode distinct isoforms, including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B).,PCSK5,PC5,PC6,PC6A,SPC6,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,PCSK5
    Molecular Weight
    101 kDa/206 kDa
    Gene ID
    5125
    UniProt
    Q92824
    Pathways
    Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones
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