Phosducin antibody (AA 1-246)

Catalog No. ABIN6145332

Product Details anti-Phosducin Antibody

Target: Phosducin (PDC)

Binding Specificity: AA 1-246

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phosducin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MEEAKSQSLE EDFEGQATHT GPKGVINDWR KFKLESQDSD SIPPSKKEIL RQMSSPQSRN GKDSKERVSR KMSIQEYELI HKEKEDENCL RKYRRQCMQD MHQKLSFGPR YGFVYELETG KQFLETIEKE LKITTIVVHI YEDGIKGCDA LNSSLTCLAA EYPIVKFCKI KASNTGAGDR FSLDVLPTLL IYKGGELISN FISVAEQFAE EFFAGDVESF LNEYGLLPER EVHVLEHTKI EEEDVE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PDC (NP_002588.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Phosducin

Target: Phosducin (PDC)

Alternative Name: PDC (PDC Products)

Synonyms: MEKA antibody, PHD antibody, PhLOP antibody, PhLP antibody, Rpr-1 antibody, Rpr1 antibody, 33DPTP antibody, RPR1 antibody, phosducin antibody, PDC antibody, Pdc antibody

Background: This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.,PDC,MEKA,PHD,PhLOP,PhLP,phosducin,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),PDC

Molecular Weight: 22 kDa/28 kDa/32 kDa

Gene ID: 5132

UniProt: P20941