PER2 antibody (AA 1-150)

Catalog No. ABIN6217063

Product Details anti-PER2 Antibody

Target: PER2 (Period Circadian Protein 2 (PER2))

Binding Specificity: AA 1-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PER2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Sequence: MNGYAEFPPS PSNPTKEPVE PQPSQVPLQE DVDMSSGSSG HETNENCSTG RDSQGSDCDD SGKELGMLVE PPDARQSPDT FSLMMAKSEH NPSTSGCSSD QSSKVDTHKE LIKTLKELKV HLPADKKAKG KASTLATLKY ALRSVKQVKA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PER2 (NP_073728.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,ChIP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PER2

Target: PER2 (Period Circadian Protein 2 (PER2))

Alternative Name: PER2 (PER2 Products)

Synonyms: FASPS antibody, FASPS1 antibody, mKIAA0347 antibody, mPer2 antibody, rPER2 antibody, gPer2 antibody, fj43b09 antibody, wu:fj43b09 antibody, period circadian regulator 2 antibody, period circadian clock 2 antibody, PER2 antibody, Per2 antibody, per2 antibody

Background: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders.,PER2,FASPS,FASPS1,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Cardiovascular,Blood,Blood Pressure regulation,PER2

Molecular Weight: 45 kDa/136 kDa

Gene ID: 8864

UniProt: O15055