RFC4 antibody (AA 204-363)

Catalog No. ABIN6146881

This anti-RFC4 antibody is a Rabbit Polyclonal antibody detecting RFC4 in WB, IF and IP. Suitable for Human.

Quick Overview for RFC4 antibody (AA 204-363) (ABIN6146881)

Target: RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RFC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-RFC4 Antibody

Binding Specificity: AA 204-363

Sequence: DKIQQQRLLD IAKKENVKIS DEGIAYLVKV SEGDLRKAIT FLQSATRLTG GKEITEKVIT DIAGVIPAEK IDGVFAACQS GSFDKLEAVV KDLIDEGHAA TQLVNQLHDV VVENNLSDKQ KSIITEKLAE VDKCLADGAD EHLQLISLCA TVMQQLSQNC

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 204-363 of human RFC4 (NP_002907.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100,IP,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RFC4

Target: RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))

Alternative Name: RFC4

Background: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.,RFC4,A1,RFC37,Epigenetics & Nuclear Signaling,RFC4

Molecular Weight: 33 kDa/39 kDa

Gene ID: 5984

UniProt: P35249

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA