SLC5A5 antibody (AA 544-643)

Catalog No. ABIN6148023

Product Details anti-SLC5A5 Antibody

Target: SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))

Binding Specificity: AA 544-643

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC5A5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: ALISCLTGPT KRSTLAPGLL WWDLARQTAS VAPKEEVAIL DDNLVKGPEE LPTGNKKPPG FLPTNEDRLF FLGQKELEGA GSWTPCVGHD GGRDQQETNL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 544-643 of human SLC5A5 (NP_000444.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:20 - 1:50

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-SLC5A5 antibody (ABIN6148023)

Yang, Yi, Zhang, He, He, Wu, Xu, Li, Fan, Zhu, Xue, Zhou: "Generation and characterization of a hypothyroidism rat model with truncated thyroid stimulating hormone receptor." in: Scientific reports, Vol. 8, Issue 1, pp. 4004, (2018) (PubMed).

Target Details for SLC5A5

Target: SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))

Alternative Name: SLC5A5 (SLC5A5 Products)

Synonyms: Na(+)/I(-) cotransporter antibody, Na(+)/I(-) symporter antibody, Nis antibody, solute carrier family 5 member 5 antibody, Slc5a5 antibody

Background: This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.,SLC5A5,NIS,TDH1,Cancer,Signal Transduction,Endocrine & Metabolism,SLC5A5

Molecular Weight: 68 kDa

Gene ID: 6528

UniProt: Q92911