UACA antibody (AA 1-90)

Catalog No. ABIN6149761

Product Details anti-UACA Antibody

Target: UACA

Binding Specificity: AA 1-90

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UACA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MKSLKSRLRR QDVPGPASSG AAAASAHAAD WNKYDDRLMK AAERGDVEKV TSILAKKGVN PGKLDVEGRS VFHVVTSKGN LECLNAILIH

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human UACA (NP_060473.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UACA

Target: UACA

Alternative Name: UACA (UACA Products)

Synonyms: NUCLING antibody, 2700059D02Rik antibody, nucling antibody, RGD1560011 antibody, uveal autoantigen with coiled-coil domains and ankyrin repeats antibody, UACA antibody, Uaca antibody

Background: Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity.,UACA,NUCLING,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,UACA

Molecular Weight: 161 kDa/162 kDa

Gene ID: 55075

UniProt: Q9BZF9

Pathways: Positive Regulation of Endopeptidase Activity