×
For best experience we recommend to activate Javascript in your browser.
AIF antibody (AA 593-606)
AIFM1
Reactivity: Human
WB, IF, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-AIF Antibody
(hide)
Target
See all AIF (AIFM1) Antibodies
AIF (AIFM1)
(Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
Binding Specificity
All epitopes for AIF antibodies
AA 593-606
Reactivity
All reactivities for AIF antibodies
Human
Host
All hosts for AIF antibodies
Rabbit
Clonality
All clonalities for AIF antibodies
Polyclonal
Conjugate
All conjugates for AIF antibodies
This AIF antibody is un-conjugated
Application
All applications for AIF antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to Apoptosis-inducing Factor (AIFM1, PDCD8).
Purification
Immunoaffinity Chromatography
Immunogen
AIFM1 antibody was raised against synthetic peptide (KDGEQHEDLNEVAK) corresponding to amino acids 593 to 606 of human AIF.
Top Product
Discover our top product AIFM1 Primary Antibody
Alternatives
(show)
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 131-230) antibody
AIFM1
Reactivity: Human, Mouse, Rat, Pig
WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
(hide)
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Buffer
PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
Target Details for AIF
(hide)
Target
AIF (AIFM1)
(Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
Alternative Name
AIFM1 / AIF (AIFM1 Products )
Synonyms
AIF antibody, CMTX4 antibody, COWCK antibody, COXPD6 antibody, PDCD8 antibody, CG7263 antibody, DmAIF antibody, Dmel\\CG7263 antibody, GB16024 antibody, DDBDRAFT_0187853 antibody, DDBDRAFT_0191137 antibody, DDB_0187853 antibody, DDB_0191137 antibody, aif antibody, pdcd8 antibody, AIFM1 antibody, PCD8 antibody, AIFsh2 antibody, Hq antibody, Pdcd8 antibody, mAIF antibody, Aif antibody, zgc:91994 antibody, apoptosis inducing factor mitochondria associated 1 antibody, allograft inflammatory factor 1 antibody, Apoptosis inducing factor antibody, apoptosis-inducing factor 1, mitochondrial antibody, apoptosis inducing factor antibody, apoptosis inducing factor, mitochondria associated 1 antibody, apoptosis-inducing factor, mitochondrion-associated, 1 antibody, apoptosis-inducing factor, mitochondrion-associated 1 antibody, AIFM1 antibody, AIF1 antibody, AIF antibody, LOC412212 antibody, aif antibody, aifm1 antibody, Aifm1 antibody
Background
Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins. A novel gene, the product of which causes chromatin condensation and DNA fragmentation, was recently identified, cloned, and designated apoptosis inducing factor (AIF). Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli. AIF is highly conserved between human and mouse and widely expressed.Synonyms: Apoptosis-inducing factor 1 mitochondrial, PDCD8, Programmed cell death protein 8
Gene ID
9131
NCBI Accession
NP_004199
UniProt
O95831
Pathways
Apoptosis , Positive Regulation of Endopeptidase Activity , Cell RedoxHomeostasis , Smooth Muscle Cell Migration , Warburg Effect
Recently viewed
(hide)