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PAR1 antibody (Internal Region)
F2R
Reactivity: Human
WB, IHC (p), EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-PAR1 Antibody
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Target
See all PAR1 (F2R) Antibodies
PAR1 (F2R)
(Coagulation Factor II (thrombin) Receptor (F2R))
Binding Specificity
All epitopes for PAR1 antibodies
Internal Region
Reactivity
All reactivities for PAR1 antibodies
Human
Host
All hosts for PAR1 antibodies
Goat
Clonality
All clonalities for PAR1 antibodies
Polyclonal
Conjugate
All conjugates for PAR1 antibodies
This PAR1 antibody is un-conjugated
Application
All applications for PAR1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Sequence
C-TRARRPESKA TNAT
Specificity
This antibody detects Thrombin receptor / F2R.
Purification
Immunoaffinity Chromatography
Immunogen
Synthetic peptide from the Internal region (near N-terminus) of the human protein sequence according to NP_001983.2
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Discover our top product F2R Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0,5 mg/mL
Buffer
Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % sodium azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for PAR1
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Target
PAR1 (F2R)
(Coagulation Factor II (thrombin) Receptor (F2R))
Alternative Name
Thrombin Receptor / F2R (F2R Products )
Synonyms
CF2R antibody, HTR antibody, PAR-1 antibody, PAR1 antibody, TR antibody, Par1 antibody, TRGPC antibody, AI482343 antibody, Cf2r antibody, ThrR antibody, Par-1 antibody, f2r-a antibody, par1 antibody, coagulation factor II thrombin receptor antibody, coagulation factor II (thrombin) receptor antibody, coagulation factor 2 (thrombin) receptor L homeolog antibody, F2R antibody, F2r antibody, f2r.L antibody
Background
Thrombin Receptor is a Proteinase-Activated Receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. Thrombin induced RANTES expression through a PAR-1 mediated pathway influences inflammatory cell migration to the synovium in patients with rheumatoid arthritis.Synonyms: CF2R, Coagulation factor II receptor, PAR-1, PAR1, Proteinase-activated receptor 1
Gene ID
2149
NCBI Accession
NP_001983
UniProt
P25116
Pathways
Nuclear Receptor Transcription Pathway , Skeletal Muscle Fiber Development , Positive Regulation of Endopeptidase Activity , Protein targeting to Nucleus
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