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Neurogranin antibody (Internal Region)
NRGN
Reactivity: Human, Mouse, Dog, Cow
WB, IHC (p), EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-Neurogranin Antibody
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Target
See all Neurogranin (NRGN) Antibodies
Neurogranin (NRGN)
Binding Specificity
All epitopes for Neurogranin antibodies
Internal Region
Reactivity
All reactivities for Neurogranin antibodies
Human, Mouse, Dog, Cow
Host
All hosts for Neurogranin antibodies
Goat
Clonality
All clonalities for Neurogranin antibodies
Polyclonal
Conjugate
All conjugates for Neurogranin antibodies
This Neurogranin antibody is un-conjugated
Application
All applications for Neurogranin antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Sequence
C-KIKSGERGRK G
Specificity
This antibody recognizes Neurogranin. Reported variants represent identical protein: NP_006167.1, NP_001119653.1
Cross-Reactivity (Details)
Species reactivity (expected):Canine (Dog) and Bovine. Species reactivity (tested):Human, Mouse and Rat.
Purification
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Immunogen
Peptide with sequence from the internal region of the protein sequence according to NP_006167.1. Genename: NRGN
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Discover our top product NRGN Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Neurogranin
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Target
Neurogranin (NRGN)
Alternative Name
Neurogranin (NRGN Products )
Synonyms
RC3 antibody, hng antibody, 0710001B06Rik antibody, AI838505 antibody, NG antibody, NG/RC3 antibody, Pss1 antibody, R75334 antibody, zgc:158686 antibody, neurogranin antibody, neurogranin (protein kinase C substrate, RC3) b antibody, NRGN antibody, Nrgn antibody, nrgnb antibody
Background
Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.Synonyms: Ng, Nrgn, Protein kinase C substrate 7.5 kDa protein, RC3
Gene ID
4900
NCBI Accession
NP_006167
UniProt
Q92686
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