Moesin antibody
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- Target See all Moesin (MSN) Antibodies
- Moesin (MSN)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Moesin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Purpose
- Mouse Monoclonal anti-Moesin (MSN492), Purified, BSA-free
- Characteristics
- This antibody recognizes 78 kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Purification
- Purified
- Immunogen
- Recombinant full-length human Moesin protein
- Clone
- MSN492
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product MSN Primary Antibody
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- Application Notes
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Does not react with rat, others not known
- Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Comment
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HT-29, CH3LC, or HUVEC cells. Uterus, Placenta, Tonsil, Melanoma, Testicular Carcinoma.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS (no BSA, no azide)
- Preservative
- Azide free
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- Target
- Moesin (MSN)
- Alternative Name
- Moesin (MSN Products)
- Synonyms
- CG10701 antibody, D17 antibody, Dmel\\CG10701 antibody, Dmoe antibody, EMR1 antibody, ERM antibody, Emr1 antibody, anon-WO03040301.155 antibody, anon-WO03040301.157 antibody, anon-WO03040301.159 antibody, anon-WO03040301.161 antibody, dMoe antibody, gma antibody, l(1)G0067 antibody, l(1)G0323 antibody, l(1)G0404 antibody, l(1)G0415 antibody, moe antibody, moesin/ezrin/radixin homolog mRNA antibody, cb567 antibody, rdx antibody, wu:fb14b03 antibody, zgc:85640 antibody, MSN antibody, C78546 antibody, moesin antibody, Moesin antibody, moesin a antibody, moesin L homeolog antibody, MSN antibody, Moe antibody, msna antibody, msn.L antibody, moes antibody, Msn antibody
- Background
- Membrane-organizing extension spike protein, Moesin/anaplastic lymphoma kinase fusion protein, MSN/ALK fusion
- Molecular Weight
- 78 kDa
- Gene ID
- 4478, 87752
- UniProt
- P26038
- Pathways
- Asymmetric Protein Localization
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