PAX7 antibody (AA 300-600)
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- Target See all PAX7 Antibodies
- PAX7 (Paired Box 7 (PAX7))
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Binding Specificity
- AA 300-600
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Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio), Chicken
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PAX7 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Purpose
- Mouse Monoclonal anti-PAX7 (PAX7/497), Purified, with BSA
- Characteristics
- The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Purification
- Purified
- Immunogen
- Recombinant fragment (aa300-600) of human PAX7 protein
- Clone
- PAX7-497
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product PAX7 Primary Antibody
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- Application Notes
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Immunohistology (frozen) 0.5-1 μg/mL
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Comment
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HeLa, Jurkat, A431, MCF-7, U2OS or NIH/3T3 cells. Rhabdomyosarcoma (RMS)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 200 μg/mL
- Buffer
- PBS/0.05 % BSA/0.05 % azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- PAX7 (Paired Box 7 (PAX7))
- Alternative Name
- PAX7 (PAX7 Products)
- Synonyms
- PAX7 antibody, HUP1 antibody, PAX7B antibody, RMS2 antibody, pax-7 antibody, PAX-7 antibody, RGD1564360 antibody, Pax-7 antibody, pax7 antibody, pax7c antibody, pax7d antibody, pax7e antibody, paired box 7 antibody, paired box protein Pax-7 antibody, paired box 7 L homeolog antibody, paired box 7a antibody, PAX7 antibody, pax7.L antibody, LOC536229 antibody, Pax7 antibody, pax7a antibody
- Background
- HUP1, Paired box gene 7, Paired box homeotic gene 7, Paired domain gene HuP1, PAX7 transcriptional factor, PAX7/FKHR fusion gene, PAX7B, RMS2
- Molecular Weight
- 57 kDa
- Gene ID
- 5081, 113253
- UniProt
- P23759
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