CDC37 antibody (AA 1-160)

Catalog No. ABIN6219857

Product Details anti-CDC37 Antibody

Target: CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))

Binding Specificity: AA 1-160

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC37 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Sequence: MVDYSVWDHI EVSDDEDETH PNIDTASLFR WRHQARVERM EQFQKEKEEL DRGCRECKRK VAECQRKLKE LEVAEGGKAE LERLQAEAQQ LRKEERSWEQ KLEEMRKKEK SMPWNVDTLS KDGFSKSMVN TKPEKTEEDS EEVREQKHKT FVEKYEKQIK

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human CDC37 (NP_008996.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:1000,IHC,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CDC37

Target: CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))

Alternative Name: CDC37 (CDC37 Products)

Synonyms: CG12019 antibody, CPDR-1 antibody, CPDR-2 antibody, DROCPDR antibody, Dmel\\CG12019 antibody, E(sev)3B antibody, cdc37 antibody, Afu4g10010 antibody, P50CDC37 antibody, p50 antibody, p50Cdc37 antibody, CG12019 gene product from transcript CG12019-RA antibody, cell division cycle 37 homolog antibody, Hsp90 co-chaperone Cdc37 antibody, Cdc37p antibody, cell division cycle 37 antibody, Cdc37 antibody, cdc37 antibody, AFUA_4G10010 antibody, CDC37 antibody

Background: The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.,CDC37,P50CDC37,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Cell Cycle,Endocrine & Metabolism,Mitochondrial metabolism,CDC37

Molecular Weight: 44 kDa

Gene ID: 11140

UniProt: Q16543