PHLDA2 antibody, ipl antibody, phlda2 antibody, BRW1C antibody, BWR1C antibody, HLDA2 antibody, IPL antibody, TSSC3 antibody, Ipl antibody, Tssc3 antibody, zgc:110459 antibody, pleckstrin homology like domain family A member 2 antibody, Pleckstrin homology-like domain family A member 2 antibody, pleckstrin homology like domain, family A, member 2 antibody, pleckstrin homology-like domain, family A, member 2 antibody, pleckstrin homology-like domain, family A, member 2 L homeolog antibody, PHLDA2 antibody, phla2 antibody, Phlda2 antibody, phlda2.L antibody, phlda2 antibody
Background
This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver.,PHLDA2,BRW1C,BWR1C,HLDA2,IPL,TSSC3,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,PHLDA2