Nckx2 antibody, AI847460 antibody, 2810021B17Rik antibody, 6330417K15Rik antibody, SLC24A2 antibody, NCKX2 antibody, NCKX antibody, solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 antibody, solute carrier family 24 member 2 antibody, Slc24a2 antibody, SLC24A2 antibody
Background
Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).