SHB antibody (AA 250-290)

Catalog No. ABIN6577402

Product Details anti-SHB Antibody

Target: SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))

Binding Specificity: AA 250-290

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 250-290 amino acids from human.

Clone: RB47168

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:25. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for SHB

Target: SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))

Alternative Name: SHB (SHB Products)

Synonyms: SHB antibody, RP11-3J10.8 antibody, bA3J10.2 antibody, RGD1565350 antibody, BC028832 antibody, SH2 domain containing adaptor protein B antibody, src homology 2 domain-containing transforming protein B antibody, SHB antibody, Shb antibody

Background: Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic- FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.

Molecular Weight: 55042

UniProt: Q15464