MAPT antibody (C-Term)
Quick Overview for MAPT antibody (C-Term) (ABIN6243259)
Target
See all MAPT AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 694-728, C-Term
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Predicted Reactivity
- B
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This MAPT antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 694-728 amino acids from the C-terminal region of human MAPT.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000. WB: 1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- MAPT (Microtubule-Associated Protein tau (MAPT))
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Alternative Name
- MAPT
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Background
- Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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Molecular Weight
- 78928
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UniProt
- P10636
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Pathways
- MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size
Target
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