CDK5R1 antibody (N-Term)

Catalog No. ABIN6243625

Product Details anti-CDK5R1 Antibody

Target: CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))

Binding Specificity: AA 30-64, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK5R1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CDK5R1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 30-64 amino acids from the N-terminal region of human CDK5R1.

Clone: RB50920

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for CDK5R1

Target: CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))

Alternative Name: CDK5R1 (CDK5R1 Products)

Synonyms: CDK5P35 antibody, CDK5R antibody, NCK5A antibody, p23 antibody, p25 antibody, p35 antibody, p35nck5a antibody, cdk5r1 antibody, zgc:92814 antibody, CDK5R1 antibody, Cdk5r antibody, P25/P35 antibody, D11Bwg0379e antibody, Xp35.1 antibody, cyclin dependent kinase 5 regulatory subunit 1 antibody, cyclin-dependent kinase 5, regulatory subunit 1b (p35) antibody, cyclin-dependent kinase 5 regulatory subunit 1 antibody, S100 calcium binding protein A9 antibody, cyclin-dependent kinase 5, regulatory subunit 1 (p35) antibody, cyclin-dependent kinase 5, regulatory subunit 1 (p35) L homeolog antibody, CDK5R1 antibody, cdk5r1b antibody, Cdk5r1 antibody, S100A9 antibody, cdk5r1.L antibody

Target Type: Viral Protein

Background: P35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.

Molecular Weight: 34060

UniProt: Q15078

Pathways: Stem Cell Maintenance, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity