FAK antibody (AA 557-587)
Quick Overview for FAK antibody (AA 557-587) (ABIN6243657)
Target
See all FAK (PTK2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 557-587
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Predicted Reactivity
- C, M, Rat, X
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This FAK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-587 amino acids from human FAK1.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000. FC: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
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Alternative Name
- FAK1
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Background
- FAK1 is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of the gene encoding FAK1 may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix.
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Molecular Weight
- 119233
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NCBI Accession
- NP_001186578, NP_722560
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UniProt
- Q05397
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Pathways
- Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Target
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