GCKR antibody (AA 87-120)

Catalog No. ABIN6243672

The Rabbit Polyclonal anti-GCKR antibody is suitable to detect GCKR in samples from Rat and Mouse. It has been validated for WB.

Quick Overview for GCKR antibody (AA 87-120) (ABIN6243672)

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCKR antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB53063

Product Details anti-GCKR Antibody

Binding Specificity: AA 87-120

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GCKR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 87-120 amino acids from human GCKR.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for GCKR

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Alternative Name: GCKR

Background: Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.

Molecular Weight: 68685

UniProt: Q14397

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus