GCKR antibody (AA 1-625)

Catalog No. ABIN7153892

Product Details anti-GCKR Antibody

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Binding Specificity: AA 1-625

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCKR antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Glucokinase regulatory protein (1-625AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GCKR

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Alternative Name: GCKR (GCKR Products)

Synonyms: FGQTL5 antibody, GKRP antibody, GLRE antibody, gckr antibody, glucokinase regulator antibody, glucokinase regulatory protein antibody, glucokinase regulator L homeolog antibody, GCKR antibody, Gckr antibody, gckr.L antibody

Background:

Background: Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.

Aliases: FGQTL5 antibody, GCK antibody, GCKR antibody, GCKR_HUMAN antibody, GKRP antibody, GLRE antibody, glucokinase (hexokinase 4) regulator antibody, Glucokinase antibody, Glucokinase regulator antibody, Glucokinase regulatory protein antibody, Hexokinase 4 regulator antibody, Hexokinase type IV antibody, Hexokinase-4 antibody, Hexokinase-D antibody, HK IV antibody, HK4 antibody, OTTHUMP00000158533 antibody

UniProt: Q14397

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus