PPP2R5B antibody (C-Term)

Catalog No. ABIN6243837

Product Details anti-PPP2R5B Antibody

Target: PPP2R5B (Protein Phosphatase 2, Regulatory Subunit B', beta (PPP2R5B))

Binding Specificity: AA 466-500, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R5B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PPP2R5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 466-500 amino acids from the C-terminal region of human PPP2R5B.

Clone: RB51478

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:25. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PPP2R5B

Target: PPP2R5B (Protein Phosphatase 2, Regulatory Subunit B', beta (PPP2R5B))

Alternative Name: PPP2R5B (PPP2R5B Products)

Synonyms: B56B antibody, PR61B antibody, B'beta antibody, BC026670 antibody, PPP2R5B antibody, ppp2r5e antibody, protein phosphatase 2 regulatory subunit B'beta antibody, protein phosphatase 2, regulatory subunit B', beta antibody, protein phosphatase 2A regulatory subunit B' antibody, protein phosphatase 2 regulatory subunit B', beta antibody, protein phosphatase 2 regulatory subunit Bbeta antibody, PPP2R5B antibody, Ppp2r5b antibody, ppp2r5b antibody, ppp2r5b.L antibody, PPP2R2B antibody

Background: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues.

Molecular Weight: 57393

UniProt: Q15173

Pathways: PI3K-Akt Signaling, ER-Nucleus Signaling