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PD-1 antibody
PDCD1
Reactivity: Human
FACS, IF, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PD-1 Antibody
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Target
See all PD-1 (PDCD1) Antibodies
PD-1 (PDCD1)
(Programmed Cell Death 1 (PDCD1))
Reactivity
All reactivities for PD-1 antibodies
Human
Host
All hosts for PD-1 antibodies
Rabbit
Clonality
All clonalities for PD-1 antibodies
Polyclonal
Conjugate
All conjugates for PD-1 antibodies
This PD-1 antibody is un-conjugated
Application
All applications for PD-1 antibodies
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
Protein A affinity chromatography
Immunogen
A full-length human protein was used as the immunogen for the PD1 antibody.
Isotype
IgG
Top Product
Discover our top product PDCD1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT Immunofluorescence: 1-2 μg/mL Flow Cytometry: 0.5-1 μg/10e6 cells in 0.1ml Titering of the PD1 antibody may be required for optimal performance.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Target Details for PD-1
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Target
PD-1 (PDCD1)
(Programmed Cell Death 1 (PDCD1))
Alternative Name
PDCD1 / PD-1 (PDCD1 Products )
Synonyms
CD279 antibody, PD-1 antibody, PD1 antibody, SLEB2 antibody, hPD-1 antibody, hPD-l antibody, Ly101 antibody, Pdc1 antibody, programmed cell death 1 antibody, PDCD1 antibody, Pdcd1 antibody
Background
PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.
Gene ID
5133
UniProt
Q15116
Pathways
Cancer Immune Checkpoints
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