ODC1 antibody
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- Target See all ODC1 Antibodies
- ODC1 (Ornithine Decarboxylase 1 (ODC1))
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Reactivity
- Human, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ODC1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Purification
- Protein G affinity chromatography
- Immunogen
- Recombinant human protein was used as the immunogen for this ODC-1 antibody.
- Clone
- SPM565
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product ODC1 Primary Antibody
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- Application Notes
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)
The optimal dilution of the Ornithine Decarboxylase antibody for each application should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Target
- ODC1 (Ornithine Decarboxylase 1 (ODC1))
- Alternative Name
- Ornithine Decarboxylase (ODC1 Products)
- Synonyms
- CG8721 antibody, Dmel\\CG8721 antibody, dodc1 antibody, odc antibody, fc54f04 antibody, fi06d08 antibody, CHUNP6922 antibody, wu:fc54f04 antibody, wu:fi06d08 antibody, odc2 antibody, xODC1 antibody, xodc2 antibody, DDBDRAFT_0204020 antibody, DDBDRAFT_0237755 antibody, DDB_0204020 antibody, DDB_0237755 antibody, ODC antibody, odc1 antibody, ODC1 antibody, Odc antibody, odc1-a antibody, Ornithine decarboxylase 1 antibody, ornithine decarboxylase 1 antibody, ornithine decarboxylase antibody, diaminopimelate decarboxylase antibody, Orn/DAP/Arg decarboxylase 2 domain-containing protein antibody, Diaminopimelate decarboxylase antibody, Ornithine decarboxylase antibody, ornithine decarboxylase 1 L homeolog antibody, ornithine decarboxylase, structural 1 antibody, Odc1 antibody, odc1 antibody, ODC1 antibody, odc antibody, RR_RS04895 antibody, ASA_RS06380 antibody, LOC100232922 antibody, odc1.L antibody, odc-1 antibody
- Background
- Recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
- Gene ID
- 4953
- UniProt
- P11926
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