LGALS13 antibody (AA 23-134)

Catalog No. ABIN6252805

Product Details anti-LGALS13 Antibody

Target: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Binding Specificity: AA 23-134

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LGALS13 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Protein G affinity chromatography

Immunogen: A human partial recombinant protein corresponding to amino acids 23-134 was used as the immunogen for the Galectin 13 antibody.

Clone: PP13-1161

Isotype: IgG2b kappa

Application Details

Application Notes: IF: 1-2 μg/mL

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

WB: 0.5-1 μg/mL

IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Titering of the Galectin 13 antibody may be required for optimal performance.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Target Details for LGALS13

Target: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Alternative Name: Galectin 13 (LGALS13 Products)

Synonyms: GAL13 antibody, PLAC8 antibody, PP13 antibody, Gal-11 antibody, Gal-13 antibody, Gal11 antibody, gal-13 antibody, galectin 13 antibody, avian beta-defensin 13 antibody, LGALS13 antibody, AvBD13 antibody

Background: It recognizes a 32  kDa protein, which is identified as homodimer of LGALS13/Galectin 13 (also known as PP13). Galectins are a family of soluble beta-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, Galectin 13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, Galectin-13 exists as a disulfide-linked homodimer. Galectin 13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for Galectin 13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.

Gene ID: 29124

UniProt: Q9UHV8