CD45RA antibody

Catalog No. ABIN6253057

Product Details anti-CD45RA Antibody

Target: CD45RA

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD45RA antibody is un-conjugated

Application: Flow Cytometry (FACS)

Characteristics: The clone OTH-74D4, a mouse monoclonal antibody, recognizes a 220 kDa cell surface isoform protein known as CD45RA of the leucocyte common antigen (LCA) of the CD45 antigen family.  The CD45RA antigen is expressed mostly on naive CD4+, CD8+, γδ+ T, and on most B and NK lymphocytes. Generally, the CD45RA antigen density decreases upon activation.

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: An EBV-transformed B cell line from a patient with MHC class II deficiency

Clone: OTH-74D4

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD45RA

Target: CD45RA

Alternative Name: CD45RA (CD45RA Products)

Synonyms: B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L-CA antibody, LCA antibody, LY5 antibody, T200 antibody, Lca antibody, RT7 antibody, protein tyrosine phosphatase, receptor type C antibody, protein tyrosine phosphatase, receptor type, C antibody, PTPRC antibody, Ptprc antibody

Background: The clone OTH-74D4, a mouse monoclonal antibody, recognizes a 220 kDa cell surface isoform protein known as CD45RA of the leucocyte common antigen (LCA) of the CD45 antigen family.  The CD45RA antigen is expressed mostly on naive CD4+, CD8+, γδ+ T, and on most B and NK lymphocytes. Generally, the CD45RA antigen density decreases upon activation.

NCBI Accession: NM_002838

UniProt: P08575