Asprosin antibody

Catalog No. ABIN6253475

Product Details

Target: Asprosin

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: anti-Asprosin (human), mAb (Birdy-2)

Characteristics: Monoclonal Antibody. Recognizes human asprosin and human fibrillin-1 (by homology). Isotype: Mouse IgG2a. Clone: Birdy-2. Application: ELISA, WB. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. Asprosin is a new fasting-induced protein hormone that targets the liver to increase plasma glucose levels. Asprosin is the C-terminal cleavage product of the protein fibrillin-1. Asprosin is secreted from white adipose tissue and increases hepatic glucose production by using cAMP as a second messenger, leading to activation of protein kinase A in the liver. Reduction of asprosin levels protect against metabolic syndrome-associated hyperinsulinism.

Purity: >95 % (SDS-PAGE)

Immunogen: Recombinant human asprosin.

Clone: Birdy-2

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

Short Term Storage: +4°C

Long Term Storage: -20°C

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

Target Details

Target: Asprosin

Synonyms: ACMICD antibody, ECTOL1 antibody, FBN antibody, GPHYSD2 antibody, MASS antibody, MFS1 antibody, OCTD antibody, SGS antibody, SSKS antibody, WMS antibody, WMS2 antibody, fibrillin 1 antibody, FBN1 antibody

Background:

Alternate Names/Synonyms: Fibrillin-1 C-terminal Cleavage Product, FBN1 C Terminal Cleavage Product

Product Description: Asprosin is a new fasting-induced protein hormone that targets the liver to increase plasma glucose levels. Asprosin is the C-terminal cleavage product of the protein fibrillin-1. Asprosin is secreted from white adipose tissue and increases hepatic glucose production by using cAMP as a second messenger, leading to activation of protein kinase A in the liver. Reduction of asprosin levels protect against metabolic syndrome-associated hyperinsulinism.