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FCGR1A antibody

FCGR1A Reactivity: Human FACS, WB, ELISA, ICC, FM Host: Mouse Monoclonal LPR-02 unconjugated
Catalog No. ABIN6253925
  • Target See all FCGR1A Antibodies
    FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
    Reactivity
    • 105
    • 25
    • 19
    • 13
    • 6
    • 5
    • 4
    • 4
    • 4
    • 1
    Human
    Host
    • 70
    • 40
    • 1
    Mouse
    Clonality
    • 69
    • 40
    • 2
    Monoclonal
    Conjugate
    • 39
    • 14
    • 13
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FCGR1A antibody is un-conjugated
    Application
    • 77
    • 64
    • 31
    • 24
    • 19
    • 19
    • 12
    • 11
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Fluorescence Microscopy (FM)
    Specificity
    CD64 reacts with the Fc gamma receptor 1 (FcγR1), a glycoprotein with a molecular weight of 72 kDa. The antigen is a high-affinity receptor for IgG and is able to bind human IgG1 and IgG3. The antigen is expressed on macrophages, monocytes, and interferon γ (IFN-γ) and Granulocyte Colony Stimulating Factor (G-CSF) stimulated neutrophils.
    Purification
    Ion exchange column
    Clone
    LPR-02
    Isotype
    IgG1
    Top Product
    Discover our top product FCGR1A Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Storage
    4 °C
  • Target
    FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
    Alternative Name
    CD64 (FCGR1A Products)
    Synonyms
    CD64 antibody, CD64A antibody, FCRI antibody, IGFR1 antibody, FcgammaRI antibody, Fcgr1 antibody, Fcgr1b antibody, AI323638 antibody, AV092959 antibody, IGGHAFC antibody, FCGR1A antibody, Fc fragment of IgG receptor Ia antibody, Fc receptor, IgG, high affinity I antibody, FCGR1A antibody, Fcgr1a antibody, Fcgr1 antibody
    Background
    Antigen distribution: This antibody binds to a CD64 epitope distinct from the ligand-binding site and from the clone 32.2 antibody to CD64 epitope. It shows especially high affinity binding to human mononuclear phagocytes and polymorphonuclear leukocytes exposed to IFN-γ or G-CSF. Its binding is not blocked in the presence of human IgG or immune complexes. Cellular Expression: Fc gamma receptor 1 on macrophages, monocytes and neutrophils.
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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