Insulin Receptor antibody (pThr1160)

Catalog No. ABIN6254022

The Rabbit Polyclonal anti-Insulin Receptor antibody has been validated for WB and ELISA. It is suitable to detect Insulin Receptor in samples from Human.

Quick Overview for Insulin Receptor antibody (pThr1160) (ABIN6254022)

Target: Insulin Receptor (INSR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Insulin Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Insulin Receptor Antibody

Binding Specificity: pThr1160

Specificity: Specific for endogenous levels of the ~95 kDa Insulin receptor phosphorylated at Thr1160. Immunolabeling is completely eliminated with λ-phosphatase treatment.

Cross-Reactivity: Human

Predicted Reactivity: bovine, canine, mouse, non-human primate, pig, rat, Xenopus

Characteristics: Our Insulin Receptor (Thr1160) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Insulin Receptor (Thr1160) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Purification: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr1160 of human insulin receptor, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Expiry Date: 12 months

Target Details for Insulin Receptor

Target: Insulin Receptor (INSR)

Alternative Name: INSR

Background:

Synonyms: CD220 antibody, HHF5 antibody, human insulin receptor antibody, Insr antibody, INSR_HUMAN antibody, Insulin receptor subunit beta antibody, IR 1 antibody, IR antibody, IR-1 antibody, IR1 antibody,

Description Logic: Our Insulin Receptor (Thr1160) rabbit polyclonal phosphospecific primary antibody is produced . It detects Insulin Receptor (Thr1160) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Gene Name Alternatives: INSR

Molecular Weight: 95 kDa

Gene ID: 3643

UniProt: P06213

Pathways: NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity