MAP3K1 antibody (pThr1402)
Quick Overview for MAP3K1 antibody (pThr1402) (ABIN6256476)
Target
See all MAP3K1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pThr1402
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Specificity
- Phospho-MEKK1 (Thr1402) Antibody detects endogenous levels of MEKK1 only when phosphorylated at Thr1400, which site historically referenced as Thr1402.
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Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human MEKK1 around the phosphorylation site of Thr1402.
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Isotype
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (AA 1307-1509) antibody
MAP3K1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (C-Term) antibodyMAP3K1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (AA 1211-1310) antibodyMAP3K1 Reactivity: Human WB, ELISA, PLA Host: Mouse Monoclonal 2F6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (AA 1077-1176) antibodyMAP3K1 Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal 2F6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (pThr1402) antibodyMAP3K1 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (pThr1383) antibodyMAP3K1 Reactivity: Human DB Host: Rabbit Polyclonal RB11308 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (AA 1145-1176), (C-Term) antibodyMAP3K1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB00999 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (C-Term) antibodyMAP3K1 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Dog WB Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (AA 1211-1310) antibodyMAP3K1 Reactivity: Human WB, IHC (p), IF, FACS Host: Mouse Monoclonal 2F6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (pThr1402) antibodyMAP3K1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
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Application Notes
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
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Expiry Date
- 12 months
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- MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))
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Alternative Name
- MAP3K1
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Background
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Description: Component of a protein kinase signal transduction cascade (PubMed:9808624). Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4 (PubMed:9808624). May phosphorylate the MAPK8/JNK1 kinase (PubMed:17761173). Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway (PubMed:9808624).
Gene: MAP3K1
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Molecular Weight
- 161 kDa
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Gene ID
- 4214
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UniProt
- Q13233
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Pathways
- MAPK Signaling, Interferon-gamma Pathway, Caspase Cascade in Apoptosis, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades
Target
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