HIST1H1E antibody (pThr18)

Catalog No. ABIN6274031

Product Details anti-HIST1H1E Antibody

Target: HIST1H1E (Histone H1.4 (HIST1H1E))

Binding Specificity: pThr18

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H1E antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Phospho-Histone H1.3 (Thr18) Antibody detects endogenous levels of Histone H1.3 only when phosphorylated at Thr18.

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human Histone H1.3 around the phosphorylation site of T18.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for HIST1H1E

Target: HIST1H1E (Histone H1.4 (HIST1H1E))

Alternative Name: HIST1H1D,HIST1H1E (HIST1H1E Products)

Synonyms: H14 antibody, H1d antibody, H1f4 antibody, Hist1h1c antibody, Hist1h1e antibody, H1.4 antibody, H1E antibody, H1F4 antibody, H1s-4 antibody, dJ221C16.5 antibody, H1-4 antibody, H1e antibody, H1var2 antibody, histone cluster 1, H1d antibody, histone cluster 1 H1 family member e antibody, histone cluster 1, H1e antibody, histone H1.4 antibody, Hist1h1d antibody, HIST1H1E antibody, Hist1h1e antibody, LOC488269 antibody

Background:

Description: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).

Gene: HIST1H1E

Molecular Weight: 30kDa

Gene ID: 3007, 3008

UniProt: P10412, P16402