ANAPC4 antibody (Internal Region)

Catalog No. ABIN6256902

Product Details anti-ANAPC4 Antibody

Target: ANAPC4 (Anaphase Promoting Complex Subunit 4 (ANAPC4))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: ANAPC4 Antibody detects endogenous levels of total ANAPC4.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ANAPC4, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for ANAPC4

Target: ANAPC4 (Anaphase Promoting Complex Subunit 4 (ANAPC4))

Alternative Name: ANAPC4 (ANAPC4 Products)

Synonyms: MGC81278 antibody, DDBDRAFT_0186409 antibody, DDBDRAFT_0234268 antibody, DDB_0186409 antibody, DDB_0234268 antibody, APC4 antibody, ANAPC4 antibody, 2610306D21Rik antibody, D5Ertd249e antibody, F18E5.150 antibody, F18E5_150 antibody, anaphase promoting complex subunit 4 antibody, anaphase promoting complex subunit 4 L homeolog antibody, Transducin/WD40 repeat-like superfamily protein antibody, Anapc4 antibody, anapc4.L antibody, ANAPC4 antibody, anapc4 antibody, APC4 antibody

Background:

Description: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Gene: ANAPC4

Molecular Weight: 92 kDa

Gene ID: 29945

UniProt: Q9UJX5

Pathways: M Phase