CLIC4 antibody (N-Term)

Catalog No. ABIN6257066

Product Details anti-CLIC4 Antibody

Target: CLIC4 (Chloride Intracellular Channel 4 (CLIC4))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLIC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: CLIC4 Antibody detects endogenous levels of total CLIC4.

Predicted Reactivity: Pig,Bovine,Sheep

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CLIC4, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CLIC4

Target: CLIC4 (Chloride Intracellular Channel 4 (CLIC4))

Alternative Name: CLIC4 (CLIC4 Products)

Synonyms: CLIC4L antibody, H1 antibody, MTCLIC antibody, huH1 antibody, p64H1 antibody, cb142 antibody, wu:fb33c05 antibody, wu:fc30h10 antibody, clic4 antibody, MGC89006 antibody, CLIC4 antibody, DKFZp459A0325 antibody, D0Jmb3 antibody, TU-74 antibody, mc3s5 antibody, mtCLIC antibody, xclic4 antibody, chloride intracellular channel 4 antibody, chloride intracellular channel 4 (mitochondrial) antibody, chloride intracellular channel 4 S homeolog antibody, CLIC4 antibody, Clic4 antibody, clic4 antibody, clic4.S antibody

Background:

Description: Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the  pH . Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).

Gene: CLIC4

Molecular Weight: 29 kDa

Gene ID: 25932

UniProt: Q9Y696