DNAL1 antibody (Internal Region)

Catalog No. ABIN6257149

Product Details anti-DNAL1 Antibody

Target: DNAL1 (Dynein, Axonemal, Light Chain 1 (DNAL1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: DNAL1 Antibody detects endogenous levels of total DNAL1.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DNAL1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DNAL1

Target: DNAL1 (Dynein, Axonemal, Light Chain 1 (DNAL1))

Alternative Name: DNAL1 (DNAL1 Products)

Synonyms: C14orf168 antibody, CILD16 antibody, 1700010H15Rik antibody, AW121714 antibody, Dnalc1 antibody, E330027P08Rik antibody, wu:fc89a04 antibody, zgc:92542 antibody, dynein axonemal light chain 1 antibody, dynein, axonemal, light chain 1 L homeolog antibody, dynein, axonemal, light chain 1 antibody, DNAL1 antibody, dnal1.L antibody, Dnal1 antibody, dnal1 antibody

Background:

Description: Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry (PubMed:21496787).

Gene: DNAL1

Molecular Weight: 22 kDa

Gene ID: 83544

UniProt: Q4LDG9