HECW2 antibody (Internal Region)
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- Target See all HECW2 Antibodies
- HECW2 (HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 2 (HECW2))
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Binding Specificity
- Internal Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HECW2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- HECW2 Antibody detects endogenous levels of total HECW2.
- Predicted Reactivity
- Sheep,Rabbit
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human HECW2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product HECW2 Primary Antibody
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- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- HECW2 (HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 2 (HECW2))
- Alternative Name
- HECW2 (HECW2 Products)
- Synonyms
- HECW2 antibody, NEDL2 antibody, A730039N16Rik antibody, D030049F17Rik antibody, Gm971 antibody, Nedl2 antibody, mKIAA1301 antibody, HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 antibody, E3 ubiquitin-protein ligase HECW2 antibody, HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2b antibody, Hecw2 antibody, HECW2 antibody, LOC531691 antibody, hecw2b antibody, hecw2 antibody
- Background
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Description: E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73 (PubMed:12890487). Involved in the regulation of mitotic metaphase/anaphase transition (PubMed:24163370).
Gene: HECW2
- Molecular Weight
- 140-150 kDa
- Gene ID
- 57520
- UniProt
- Q9P2P5
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