GNAT1 antibody (Internal Region)
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- Target See all GNAT1 Antibodies
- GNAT1 (Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GNAT1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- GNAT1 Antibody detects endogenous levels of total GNAT1.
- Predicted Reactivity
- Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human GNAT1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product GNAT1 Primary Antibody
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- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- GNAT1 (Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1))
- Alternative Name
- GNAT1 (GNAT1 Products)
- Synonyms
- GNAT1 antibody, gbt1 antibody, gnatr antibody, csnbad3 antibody, CSNBAD3 antibody, GBT1 antibody, GNATR antibody, wu:fk56e06 antibody, Gnat-1 antibody, Ird1 antibody, Ird2 antibody, Tralpha antibody, irdc antibody, irdr antibody, transducin antibody, G protein subunit alpha transducin 1 antibody, guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 antibody, guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 S homeolog antibody, guanine nucleotide binding protein, alpha transducing 1 antibody, GNAT1 antibody, gnat1 antibody, Gnat1 antibody, gnat1.S antibody
- Background
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Description: Functions as signal transducer for the rod photoreceptor RHO. Required for normal RHO-mediated light perception by the retina (PubMed:22190596). Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs), such as the photoreceptor RHO. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Activated RHO promotes GDP release and GTP binding. Signaling is mediated via downstream effector proteins, such as cGMP-phosphodiesterase (By similarity).
Gene: GNAT1
- Molecular Weight
- 36 kDa
- Gene ID
- 2779
- UniProt
- P11488
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Phototransduction
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