MLZE antibody (Internal Region)

Catalog No. ABIN6258286

Product Details anti-MLZE Antibody

Target: MLZE (Melanomaderived Leucine Zipper Extra-Nuclear Factor (MLZE))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLZE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: GSDMC Antibody detects endogenous levels of total GSDMC.

Predicted Reactivity: Bovine,Sheep

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GSDMC, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MLZE

Target: MLZE (Melanomaderived Leucine Zipper Extra-Nuclear Factor (MLZE))

Alternative Name: GSDMC (MLZE Products)

Synonyms: Gsdmc1 antibody, Mlze antibody, MLZE antibody, gasdermin C antibody, Gsdmc antibody, GSDMC antibody

Background:

Description: The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable).

Gene: GSDMC

Molecular Weight: 58 kDa

Gene ID: 56169

UniProt: Q9BYG8